Descrição: Descrição: Descrição: C:\Users\Luis\Desktop\DSC00377.JPG

 

 

 

 Luís Filipe Meira Machado

Associate Professor with Habilitation, Department of Mathematics

University of Minho, Portugal


Main Interest Areas

·      Survival Analysis

·      Multi-state Models

·      Generalized Additive Models.

·      Nonparametric Estimation

·      Computational Statistics

·      Machine Learning

·      Copula functions

·      ROC curves

·      R programming


Work Institution

Associate Professor at the Department of Mathematics of Minho University.

 

Contact

Tel.:  +351 253510443/400
Fax:  +351 253510401
Email:  
lmachado@math.uminho.pt
Adress:  Department of Mathematics, University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal
 

 

Academic Degrees

·      BSc in Mathematics, Minho University, July 1992.

·      MSc in Mathematics, Lisbon University, February 1998.

·      Postgraduate studies in 'Statistics' (DEA-Diploma de Estudios Avanzados), Santiago de Compostela University, September 2002.

·      PhD in Statistics Santiago de Compostela University, December 2005.

 

Academic Positions

·      1991-1993 Public School Teacher, “D. Sancho I” high School. Vila Nova de Famalicão, Portugal.

·      1993-1998 Junior Teaching Assistant, Department of Mathematics for Science and Technology.

·      1998- Senior Teaching Assistant, Department of Mathematics for Science and Technology.

·      1993- 2002 Member of the Mathematics Research Centre, University of Minho, Portugal.

·      2002- Member of the Research Centre Officina Mathematica, University of Minho, Portugal.

·      2006-2009 Assistant Professor, Department of Mathematics for Science and Technology of Minho University.

·      2009- Assistant Professor, Department of Mathematics and Applications.

·      2021- Associate Professor with Habilitation, Department of Mathematics.

 

Teaching Experience

·      Tutorials on Linear Algebra and Analytical Geometry, Analysis, Advanced Analysis, and Statistics, to first
degree Engineering Courses, University of Minho, Portugal.

·      Lectures on Analysis to first degree Engineering Courses, University of Minho, Portugal.

·      Lectures on Survival Analysis to the course “Specialization on decision support techniques: Statistics and
Operational Research”, University of Minho, Portugal (2003).

·      Lectures on Nonparametric tests to the course “Specialization on decision support techniques: Statistics and
Operational Research”, University of Minho, Portugal (2003).

·      Lectures on Survival Analysis to the Master “Master de Bioestadística, USC”.

·      Lectures on Survival Analysis, Epidemiological data analysis and Mathematical Statistics, to the first degree course in Applied Mathematics. Lectures on Computational Statistics to the Master “Mestrado em Estatística para a Ciência de Dados”.

·      Professor, Master in Statistics, Department of Mathematics for Science and Technology, where he taught the following courses: Analysis of Clinical and Epidemiological Data, Survival Analysis, Computational Statistics.

·      Professor of the first Degree course in Applied Mathematics where he taught the following courses: Epidemiologic Data Analysis, Survival Analysis, Statistical Mathematics, Temporal and Spatial Statistics.

·             Teacher of the First Degree Course in Applied Statistics where he taught the following courses: Methods in Biostatistics, Statistics and Probability 2, Oficina 2, Oficina 3, Stochastic Processes, etc.

·             Teacher of the Master Course in Statistics where he taught the following courses: Survival Analysis, Computational Statistics, Mathematical Statistics, Statistical Inference, Bayesian Statistics and Applications.

 

Current Research Work

[article] Luís Meira-Machado, Jacobo de Uña-Álvarez and Carmen Cadarso-Suárez. Nonparametric estimation of transition probabilities in a non-Markov Illness-death Model. Lifetime Data Analysis 2006, 12:325-344.

[article] Luís Meira-Machado, Carmen Cadarso-Suárez and Jacobo de Uña-Álvarez. tdc.msm: An R library for the analysis of multi-state survival data. Computer Methods and Programs in Biomedicine 2007, 86:131-140.

[article] Jacobo de Uña-Álvarez and Luís Meira-Machado. A simple estimator of the bivariate distribution function for censored gap times. Statistics and Probability Letters 2008, 78:2440-2445.

[article] Luís Meira-Machado, Jacobo de Uña-Álvarez, Carmen Cadarso-Suárez, Per Kragh Andersen. Multi-state models for the analysis of time to event data”. Statistical Methods in Medical Research, 2009, 18:195-222.

[article] Carmen Cadarso-Suárez, Luís Meira-Machado, Thomas Kneib and Francisco Gude. Flexible hazard ratio curves for continuous predictors in multi-state models: a P-spline approach. Statistical Modelling, 2010, 10:291-314.

[article] Luís Meira-Machado, Jacobo de Uña-Álvarez, Carmen Cadarso-Suárez. Inference in the progressive three-state model.” International Journal of Mathematical models and Methods in Applied Sciences, 2008, 2:447-454.

[article] Ana Paula Amorim, Jacobo de Uña-Álvarez, Luís Meira-Machado. Presmoothing the transition probabilities in the illness-death model, Statistics & Probability Letters, 2011, 81(7), 797-806

[article] Luís Meira-Machado and Javier Roca-Pardiñas. p3state.msm: Analyzing survival data from an illness-death model. Journal of Statistical Software, 2011, 38(3), 1-18.

[article] Ingrid Van Keilegom, Jacobo de Uña-Álvarez and Luís Meira-Machado. Nonparametric location-scale models for successive survival times under dependent censoring. Journal of Statistical Planning and Inference, 2011, 141: 1118-1131.

[article] Luís Meira-Machado. Inference for non-Markov multi-state models: An overview. Revstat Volume 9, Number 1, March 2011.

[article] Luís Meira-Machado. O estimador de Kaplan-Meier: Novos desenvolvimentos e aplicações no contexto da análise de sobrevivência multiestado. Boletim SPE, Outono 2011, 56-62.

[article] Ana Moreira and Luís Meira-Machado. survivalBIV: Estimation of the Bivariate Distribution Function for Sequentially Ordered Events Under Univariate Censoring. Journal of Statistical Software, 2012, 46(13), 1-16.

[article] Luís Meira-Machado and Susana Faria. A simulation study comparing modeling approaches in an illness-death multi-state model. Communications in Statistics - Simulation and Computation. 2014, 43(5): 929-946.

[article] Luís Meira-Machado, Javier Roca-Pardiñas, Ingrid Van Keilegon and Carmen Cadarso-Suárez. Bandwidth selection for the estimation of transition probabilities in the location-scale progressive three-state model. Computational Statistics: Volume 28, Issue 5 (2013), 2185-2210.

[article] Ana Moreira, Jacobo de Uña-Álvarez and Luís Meira-Machado. Presmoothing the Aalen-Johansen estimator of transition probabilities. Electronic Journal of Statistics. Volume 7 (2013), 1491-1516.

[article] Luís Meira-Machado, Carmen Cadarso-Suárez, Francisco Gude and Artur Araújo. smoothHR: an R package for pointwise nonparametric estimation of hazard ratio curves of continuous predictors. Computational and Mathematical Methods in Medicine. vol. 2013, Article ID 745742, 11 pages, 2013. doi:10.1155/2013/745742.

[article] Carla Moreira, Jacobo de Uña-Álvarez and Luís Meira-Machado. Nonparametric regression with doubly truncated data. Computational Statistics and Data Analysis. Volume 93, January 2016, Pages 294–307. http://dx.doi.org/10.1016/j.csda.2014.03.017.

[article] Artur Araújo, Luís Meira-Machado, Javier Roca-Pardiñas. TPmsm: Estimation of the transition probabilities in 3-state models. Journal of Statistical Software. 62(4).

[article] Luís Meira-Machado, Jacobo de Uña-Álvarez and Somnath Datta. Nonparametric Estimation of Conditional Transition Probabilities in a non-Markov Illness-death Model. Computational Statistics, 2015, 30:377-397.  DOI: 10.1007/s00180-014-0538-6.

[article] Jacobo de Uña-Álvarez and Luís Meira-Machado. Nonparametric estimation of transition probabilities in the non-Markov illness-death model: a comparative study. Biometrics. DOI: 10.1111/biom.12288. Volume 71, Issue 2, pages 364–375, June 2015.

[article] María Xosé Rodríguez-Álvarez, Luís Meira-Machado, Emad Abu-Assi, Sergio Raposeiras-Roubín. Nonparametric estimation of time-dependent ROC curves conditional on a continuous covariate. Statistics in Medicine. 2016, 35(7):1090-1102. doi: 10.1002/sim.6769.

[article] Luís Meira-Machado, Marta Sestelo, Andreia Gonçalves. Nonparametric estimation of the survival function for ordered multivariate failure time data: a comparative study. Biometrical Journal. Volume 58, Issue 3, pages 623-634, May 2016.

[article] Marta Sestelo, Nora M. Villanueva, Luis Meira-Machado and Javier Roca-Pardiñas. FWDselect: An R Package for Variable Selection in Regression Models. R Journal. Volume 18, Issue 1, pages 132-148, 2016.

[article] Luís Meira-Machado. Smoothed landmark estimators of the transition probabilities. SORT 40 (2) July-December 2016, 1-24.

[article] Luís Meira-Machado and Marta Sestelo. condSURV: An R Package for the Estimation of the Conditional Survival Function for Ordered Multivariate FailureTime Data, R Journal. Volume 8, Issue 2, pages 460-473, 2016.

[article] Ana Moreira, Artur Araújo and Luís Meira-Machado. Estimation of the bivariate distribution function for censored gap times. Communications in Statistics – Simulation and Computation, DOI:10.1080/03610918.2014.963609. 2017, 46(1), 275-300.

[article] Irantzu Barrio, Maria Xosé Rodríguez-Álvarez, Luis Meira-Machado, Cristobal Esteban, Inmaculada Arostegui. Comparison of two discrimination indexes in the polycothomisation of continuous predictors in time-to-event studies. SORT, Volume 41 (1), January-June 2017.

[article] Marta Sestelo, Nora Villanueva, Luís Meira-Machado, Javier Roca-Pardiñas, "npregfast: An R Package for Nonparametric Estimation and Inference in Life Sciences", Jornal of Statístical Software, 2017, 82(12), pages 1-27.

[article] Carla Moreira, Luís Meira-Machado, Maria João Fonseca, Ana Cristina Santos. Body mass index transitions during childhood: a multiple-state model approach. Revue d'Épidémiologie et de Santé Publique, Volume 66, Supplement 5, July 2018, Page S274.

[article] D. Costa, Helena Silva, A. Célia Caetano, Luís Meira-Machado, C. Rolanda, R. Gonçalves, D. Fernandes. Effectiveness of a practical nutritional intervention in advanced liver disease: A prospective study. Journal of Hepatology 68:S470-S471 · April 2018.

[article] Carla Moreira, Luís Meira-Machado, Maria João Fonseca, Ana Cristina Santos. A multi-state model for analysing transitions between body mass index categories during childhood - Generation XXI birth cohort study. American Journal of Epidemiology, 2019, 188(2), 305-313.

[article] José Ferreira, Nannan Song, Margarida Machado; Luís Meira-Machado, André Correia, Ana Reis. Fatigue and microgap behaviour of a three-unit implant-fixed dental prosthesis combining conventional and dynamic abutments. Journal of Medical Engineering and Technology, 2018, 42(5), 397-405.

[article] Luís Meira-Machado, Gustavo Soutinho. Análise de Dados Multiestado: aplicação a uma base de dados de cancro da mama. Boletim SPE, 2019, 21-29.

[article] Nora Villanueva, Marta Sestelo, Luís Meira-Machado. A Method for Determining Groups in Multiple Survival Curves. Statistics in Medicine, 2019, 38(5), 866-877.

[article] Luís Meira-Machado, Marta Sestelo, Estimation in the progressive illness-death model: a nonexhaustive review. Biometrical Journal, 2019, Volume 61, Issue 2, 245-263.

[article] Gustavo Soutinho, Luís Meira-Machado, Pedro Oliveira. A comparison of presmoothing methods in the estimation of transition probabilities.  Communications in Statistics - Simulation and Computation, 2020. DOI: 10.1080/03610918.2020.1762895.

[article] Gustavo Soutinho, Luís Meira-Machado. Estimation of the Transition Probabilities in Multi-state Survival Data: New Developments and Practical Recommendations, WSEAS Transactions on Mathematics, 2020, Volume 19, 353-366.

[article] Paula Lopes, Pedro Campos, Luis Meira-Machado. Survival Analysis of Organizational Networks - An Exploratory Study, arXiv 2020, http://arxiv.org/abs/2005.01481.

[article] Gustavo Soutinho e Luís Meira-Machado,  "Some of the most common copulas for simulating complex survival data", International Journal of Mathematics and Computers in Simulation, ISSN: 1998-0159, Volume 14, 2020. DOI: 10.46300/9102.2020.14.5

[article] Joana Ferreira, Alexandre Carneiro, Pedro Cunha, Armando Mansilha, Isabel Vila, Cristina Cunha, Cristina Silva, Adhemar Longatto-Filho, Maria Correia-Neves, Gustavo Soutinho, Luís Meira-Machado, Amilcar Mesquita, Jorge Cotter,  "Sarcopenia and Atherosclerotic Occlusive Disease: How Much We Know and What We Need to Know About this Association?", Artery Research, , Volume 26, 2020. DOI: https://doi.org/10.2991/artres.k.201209.072

[article] Ana Paula Amorim, Emília Athayde, Cecília Castro, Marta Susana Ferreira, A Manuela Gonçalves, Raquel Menezes, Maria Conceição Serra, Susana Faria, Luís Meira-Machado, Inês Sousa, Carla Maria Gonçalves Macedo Moreira. "UM departamento com ESTATÍSTICA", Boletim SPE, Outono 2020, 44-47.

[article] Susana Pedras, Luís Meira-Machado, André Couto-Carvalho, Rui Morais Carvalho, M. Graça Pereira, "Anxiety And/Or Depression: Which Symptoms Contribute to Adverse Clinical Outcomes After Amputation?", Journal of Mental Health, 2020. https://doi.org/10.1080/09638237.2020.1836554

[article] Nora M. Villanueva, Marta Sestelo, Luis Meira-Machado and Javier Roca-Pardiñas. clustcurv: An R Package for Determining Groups in Multiple Curves. R Journal, Vol. 13/1, June 2021.

[article] José Ferreira, Luís Meira-Machado, José Manuel Oliveira, João Carlos Ramos. Effect of crown-to-implant ratio and crown height space on marginal bone stress: A finite element analysis. International Journal of Implant Dentistry, 2021 https://doi.org/10.1186/s40729-021-00368-1.

[article] Gustavo Soutinho, Marta Sestelo, Luis Meira-Machado. survidm: survidm: An R package for Inference and Prediction in an Illness-Death Model. R Journal, 2021 (Accepted).

[article] Gustavo Soutinho, Luis Meira-Machado. Methods for checking the Markov condition in multi-state survival data. Computational Statistics, 2021. https://doi.org/10.1007/s00180-021-01139-7.

 

 

 

 

 

 

 

 

 

 

 

[Book Chapter] N. Amorim, A. Ferreira, L. Meira-Machado, “Micro-analysis of mortality in urban areas: The parish of Oliveira in Guimarães between the 18th and 20th centuries”. Title of the book “New Approaches to Death in Cities During the Health Transition”, Editors names: Diego Ramiro Fariñas and Michel Oris, Springer-Verlag, 2016 (pages 77-96). ISBN 978-3-319-43002-7.

 

[Books] Luís Meira-Machado e Gustavo Soutinho, “Proceedings of the 34th International Workshop on Statistical Modelling Volume I”, 2019 (332 páginas). ISBN: 978-989-20-9528-8.

 

[Books] Luís Meira-Machado e Gustavo Soutinho, “Proceedings of the 34th International Workshop on Statistical Modelling Volume II”, 2019 (444 páginas). ISBN: 978-989-20-9630-8

 

[Books] Arminda Gonçalves, Inês Sousa, Luís Meira-Machado, Raquel Menezes, Susana Faria. XX Jornadas de Classificação e Análise de Dados (JOCLAD2013) – Livro de Resumos (ISBN: 978-989-20-3771-4). Produzido por Instituto Nacional de Estatística.

 

[Books] Arminda Gonçalves, Inês Sousa, Luís Meira-Machado, Paulo Pereira, Raquel Menezes, Susana Faria. (2012). Programme and Book of Abstracts - VI International Workshop on Spatio-Temporal Modelling.

 

[CD-ROM] Arminda Gonçalves, Inês Sousa, Luís Meira-Machado, Paulo Pereira, Raquel Menezes, Susana Faria. CD-ROM with Proceedings of the VI International Workshop on Spatio-Temporal Modelling (ISBN: 978-989-97939-0-3).

 


Talks and Presentations

[talk] “Suavização em análise de sobrevivência. Extensões do modelo de Cox”. Department of Mathematics for Science and Technology. University of Minho, Portugal.October, 2002.

[talk] “Alternatives to Cox model in multi-state models”. Department of Statistics and Operational Research. University of Vigo, Spain. June, 2003.

[talk] “Non-parametric estimation of the transition probabilities in an illness-death model”. Department of Statistics and Operational Research. University of Vigo, Spain. Mars, 2005.

[talk] “Estimation of transition probabilities in a non-Markov illness-death model”. International Seminar on Multi-state Models. University of Vigo, Spain. May, 2005.

[talk] “Multi-state models for biomedical research”. Department of Mathematics for Science and Technology. University of Minho, Portugal. January, 2006.

[talk] “New Methods in Multi-state Models”. Department of Mathematics. Instituto Superior Técnico, Portugal. February, 2007.

[talk] “Flexible modelling of hazard ratio curves in Multi-state Models”. Departamento de Matemática para a Ciência e Tecnologia. University of Minho, Portugal. February 2008.

[invited] “Inference in multi-state survival data”. Invited Speaker in II Mathematical Iberian Meeting. Spain, Badajoz, 3-5th October  2008.

[chair] “Meeting SPE/CIM, com a colaboração do CEAUL, in Survival Analysis”, Lisboa, Portugal, November 27, 2009.

[invited]New methods in multi-state models: the three-state model”. Invited Speaker of the workshop StaM2010 “Statistical Modelling: Challenges in Health”, Lisboa, Portugal, 9-12 May 2010.

[talk] “Inference in the progressive three-state model”. Departamento de Estatística e Investigação Operacional. University of Vigo, Spain. September 2010.

[invited] “New methods for the analysis of multi-state survival data”. Applied Stochastic Models and Data Analysis (ASMDA2011). Special Session: Event Time Data Analysis. Rome, Italy, 7-10 June 2011

[talk] An R Package for the inference in a multi-state illness-death model”, III Jornadas de Usuários de R, Madrid, Espanha, November 17-18, 2011.

[invited] Presmoothing the Aalen-Johansen in an illness-Death model”, Invited talk in the 4th International Conference of the ERCIM Working Group on Computing & Statistics, London, England, December 17-19, 2011.

[talk] “Estimation of Conditional Transition Probabilities in a non-Markov Illness-death Model”, 8th World Congress in Probability and Statistics, Istanbul, Turquey, July 9-14, 2012.

[invited] Estimation of conditional transition probabilities in non-Markov multi-state models”, Invited talk in the 5th International Conference of the ERCIM Working Group on Computing & Statistics, Oviedo, Spain, December 1-3, 2012.

[invited] “Dynamic prediction for multi-state survival data”, Invited talk in the 29th European Meeting of Statisticians, Budapest, Hungry, July 20-25, 2013.

[invited] “Estimation of the transition probabilities in the illness-death model”, 7th International Conference of the ERCIM WG on Computational and Methodological Statistics (ERCIM 2014), Pisa, Italy, 6-8 December, 2014.

[invited] “Nonparametric estimation of the conditional survival function for ordered multivariate failure time data”, Invited talk in the 8th International Conference of the ERCIM Working Group on Computing & Statistics, London, England, December 12-14, 2015.

[invited] Estimation of multivariate distributions in censored gap times”, Invited talk in the 9th International Conference of the ERCIM Working Group on Computing & Statistics, Seville, Spain, December 9-11, 2016.

[invited] “Modelos matemáticos para análise da epidemiologia de delirium", 12º Congresso Nacional de Psiquiatria, Vilamoura, Portugal, November 9-12.

[invited] A utilização da (Bio)Estatística em problemas de Investigação das Ciências da Saúde”, 2º Encontro de Ciência, 3-4 de Março de 2017, Vila Nova de Famalicão (http://eccmfamalicao2017.wixsite.com/cfaevnf)

[invited] Estimation of the transition probabilities in non-Markov models: new contributions and software development”, 38th Annual Conference of the International Society for Clinical Biostatistics, Vigo, Spain, July 9-13, 2017. URL: http://iscb2017.info/?fwp=10&fwl=2.

[invited] Dynamic predictions in multi-state models: the illness-death model, V WASA - Workshop em Análise de Sobrevivência e Aplicações”. Universidade Federal da Bahia, Salvador, Brasil, 28 de Fevereiro a 2 de Março de 2018. URL: http://www.redeabe.org.br/wasa2017/paginas/conferencias-.

[invited] Analysis of survival data with multiple events: the illness-death model”, One Day Meeting on Statistics and Applied Probability, Universidade do Minho, Guimarães, Portugal, 4 de Outubro de 2019.

[invited] Methods for checking the Markov condition in multi-state survival data”, 12nd International Conference of the ERCIM WG on Computational and Methodological Statistics (ERCIM 2019), session “New methodologies and advances in survival and reliability” (organized by Juan Eloy Ruiz-Castro), University of London, 14-16 December 2019.

 

 

 

Software

·     An R package, called survidm developed to provide estimation of several quantities of interest in multi-state models (transition probabilities, occupation probabilities, cumulative incidence functions and sojourn distributions). https://CRAN.R-project.org/package=survidm 

·     An R package, called condSURV developed to provide the estimation of the conditional survival function.

·     An R package, called TP.idm developed to provide the estimation of transition probabilities for the illness-death model.

·     An R package, called p3state.msm developed for the analysis of the illness-death multi-state survival data.

·     An R package, called survivalBIV developed for the estimation of the bivariate distribution function for sequentially ordered events under univariate censoring.

·     An R library, called tdc.msm, developed for the analysis of multi-state survival data.

·     An R library, called genSurv, for the generation of survival data arising from a progressive illness-death model.

·     An R library called TPmsm, for obtaining estimates of the transition probabilities in 3-state multi-state models.

·     An R library called smoothHR, for obtaining flexible hazard ratio curves with confidence bands when considering a reference value.

·     An R package called presmTP, for obtaining presmoothed estimates of the transition probabilities.

·     Software developed for SIC Portuguese Television (with Fernando Fontes and Paulo Pereira).

 

 

Proceedings

 

[i]. Luís Meira-Machado, Carmen Cadarso-Suárez, Jacobo de Uña-Àlvarez, “Alternatives to the Cox model in Multi-state models”. I Congresso de Estatística e Investigação Operacional da Galiza e Norte de Portugal VII Congreso Galego de Estatística e Investigación de Operacións; Guimarães, Portugal, 2005.

 

[ii]. Luís Meira-Machado, “Estimation of transition probabilities in multi-state survival data”. International Conference on Interdisciplinary Mathematical & Statistical Techniques, Tomar, Portugal, 2006.

 

[iii]. Luís Meira-Machado, “Análise de dados de cancro do intestino utilizando modelos de estados múltiplos. XIV Congresso Anual da Sociedade Portuguesa de Estatística, Covilhã, Portugal, 2006.

 

[iv]. Luís Meira-Machado and Jacobo de Uña-Álvarez, “Estimation of the bivariate distribution function for censored gap times. XI Conferência Espanhola e Primeiro Encontro Ibero Americano de Biometria, Salamanca, Spain, 2007.

 

[v]. Luís Meira-Machado, “Inference in Multi-state survival data”. II Iberian Mathematical Meeting, session “Statistics and Biometry”, Badajoz, Spain, 3-5 October,  2008.

 

[vi]. Luís Meira-Machado, Carmen Cadarso-Suárez and Jacobo de Uña-Álvarez, “Inference in Multi-state survival data”. The 13th WSEAS International Conference on APPLIED MATHEMATICS, pp. 123-128. Tenerife, Spain, 2008.

 

[vii]. Luís Meira-Machado, Javier Roca-Pardiñas, “p3state.msm: software for the analysis of multi-state survival data”. IX Congreso Galego de Estatística e Investigación de Operacións, pp. 285-290. Ourense, Spain, 2009.

 

[viii]. Ana Moreira, Luís Meira-Machado, “Available software for the analysis of multi-state survival data”, XXXII Congreso Nacional de Estadística e Investigación Operativa, pp. 1-13. Coruña, Spain, September 14-17, 2010.

 

[ix]. Luís Meira-Machado, Ana Moreira, “Estimation of the Bivariate Distribution Function for Censored Gap Times”. 19th International Conference on Computational Statistics, pp. 1367-1374. Paris, France, August 22-27, 2010.

 

[x]. Ana Moreira and Luís Meira-Machado, “An R Package for the Estimation of the Bivariate Distribution for Censored Gap Times”. 26th International Workshop on Statistical Modelling (IWSM2011). Universitat de València July 11-15th, 2011.

 

[xi]. Norberta Amorim, Antero Ferreira, Luís Meira-Machado, “Micro-analysis of mortality in urban areas The parish of Oliveira in Guimarães between the 18th and 20th century”. Seminar on New Approaches to Death in Cities during the Health Transition, Sevilha, Spain, December 15-16, 2011.

 

[xii]. Ana Moreira, Luís Meira-Machado, “Conditional Estimation of the Bivariate Distribution Under Dependent Right Censoring”. 27th International Workshop on Statistical Modelling IWSM'27, Prague, Czech Republic, July 16-20, 2012.

 

[xiii]. Ana Moreira, Artur Agostinho Araújo, Luís Meira-Machado, “Estimation of the Bivariate Distribution Function: a Comparative Study”. 27th International Workshop on Statistical Modelling IWSM'27, Prague, Czech Republic, July 16-20, 2012.

 

[xiv]. Ana Moreira, Luís Meira-Machado, “Estimation of the conditional survival function for successive survival times”. 28th International Workshop on Statistical Modelling IWSM'28, Palermo, Italy, July 8-12, 2013.

 

[xv]. Andreia Gonçalves,  Luís Meira-Machado, Marta Sestelo, “Estimação da Função de Sobrevivência em dados de eventos recorrentes com censura pela direita”. XXII Congresso da Sociedade Portuguesa de Estatística, Ria Formosa, 7 a 10 de Outubro de 2015.

 

[xvi]. Luís Meira-Machado, Marta Sestelo, Andreia Gonçalves, “Nonparametric estimation of the survival function for ordered multivariate failure time data: a comparative study”, Proceedings of the 30th International Workshop on Statistical Modelling IWSM'30, Linz, Austria, July 5-10, 2015.

 

[xvii]. Luís Meira-Machado, “Presmoothed Landmark estimators of the transition probabilities”. Proceedings of the 31th International Workshop on Statistical Modelling IWSM'31, Rennes, France, July 4-8, 2016.

 

[xviii]. Luís Meira-Machado, “Estimation of multivariate distributions for recurrent event data”. Proceedings of the 32th International Workshop on Statistical Modelling IWSM'32, Groningen, Netherlands, July 2-7, 2017.

 

[xix]. Carla Moreira, Luís Meira-Machado, Maria João Fonseca, Ana Cristina Santos. Body mass index transitions during childhood: a multiple-state model approach. Revue d'Épidémiologie et de Santé Publique, Volume 66, Supplement 5, July 2018, Page S274.

 

[xx]. Luís Meira-Machado, Marta Sestelo, “An R package for Inference and Prediction in an Illness-Death Model”. Proceedings of the 33rd International Workshop on Statistical Modelling IWSM'33, Bristol, UK, July 16-20, 2018.

 

[xxi]. Luís Meira-Machado, Marta Sestelo, “An R package for Inference and Prediction in an Illness-Death Model”. Proceedings of the 33rd International Workshop on Statistical Modelling IWSM'33, Bristol, UK, July 16-20, 2018.

 

[xxii]. Nora M. Villanueva, Marta Sestelo, Luís Meira-Machado, “An R package for Determining Groups in Multiple Survival Curves”. Proceedings of the 33rd International Workshop on Statistical Modelling IWSM'33, Bristol, UK, July 16-20, 2018.

 

[xxiii]. Gustavo Soutinho, Luís Meira-Machado, Pedro Oliveira, “A comparison of Presmoothing methods in the estimation of Transition Probabilities”, III Encontro Luso-Galaico de Biometria (EBio2018), Aveiro, Portugal 28-30 June 2018, pp 53-56.

 

[xxiv]. Gustavo Soutinho, Luís Meira-Machado, Pedro Oliveira, “Methods for checking the Markov condition in multi-state survival data”. Proceedings of the 34th International Workshop on Statistical Modelling IWSM'34, Guimarães, Portugal, July 7-12, 2019.

 

[xxv]. Carla Moreira, Luís Meira-Machado, Maria João Fonseca, Ana Cristina Santos, “Multi-level modelling of longitudinal child growth data: a comparison of growth models in the Generation XXI birth cohort”. Proceedings of the 34th International Workshop on Statistical Modelling IWSM'34, Guimarães, Portugal, July 7-12, 2019.

 

[xxvi]. Gustavo Soutinho, Luís Meira-Machado, Pedro Oliveira, Estimation of the Transition Probabilities condition on repeated measures in Multi-state models. Proceedings of the 35th International Workshop on Statistical Modelling IWSM'35, Bilbao, Spain,

 

 

 

Other Research Reports and Thesis

·      Estudo das Categorias Extensivas e Modulares. (MSc thesis, University of Lisbon, 1998).

·      Una revisión sobre la suavización en el modelo de hazares proporcionales. (Document for obtaining the diploma of Advanced Studies in Statistics, University of Santiago de Compostela, 2002). 

·      Multi-state Models for Biomedical Research: New Contributions in Statistical Modelling, Software Development, and Applications. (PhD thesis, University of Santiago de Compostela, 2005).

·      Luís Meira-Machado, Jacobo de Uña-Álvarez, Carmen Cadarso-Suárez, Per Kragh Andersen. Multi-state models for the analysis of time to event data. Research Report 07/01 2007, Department of Biostatistics, University of Copenhagen. (this file can be downloaded from: http://biostat.ku.dk/reports/2007/researchreport07-1.pdf)

·      Ingrid Van Keilegom, Jacobo de Uña-Álvarez and Luís Meira-Machado. Nonparametric location-scale models for successive survival times under dependent censoring. Discussion paper (this file can be downloaded from: http://sites.uclouvain.be/IAP-Stat-Phase-V-VI/ISBApub/ISBAdp.html#2008).

·      Luís Meira-Machado and Javier Roca-Pardiñas. p3state.msm: Analyzing survival data from an illness-death model. Research Report, Department of Statistics and Operations Research, University of Vigo, Spain.

 

Supervisions

 

[Post-doc] Carla Maria Gonçalves Moreira, “New developments in the statistical analysis of survival data”, started in 01/01/2011.

[Post-doc] Marta Sestelo Pérez, “New developments and software in flexible regression models”, started in 01/09/2014.

[Post-doc] Maria Xosé Rodrigues Álvarez, beginning in September 2013, end in May 2016 (with Javier Roca-Pardiñas (Univ. Vigo) and Thomas Kneib (Univ. Göttingen)).

 

 

[PhD] Ana Cristina Moreira, “Métodos para a análise de dados de sobrevivência multiestado”, University of Minho. Concluded in May 2014.

[PhD] Gustavo Soutinho, “Statistical analysis of complex survival data: new contributions in statistical inference, software development and biomedical applications”. In progress.

 

[Other] Liliana Rodrigues Coelho, “Métodos flexíveis em modelos de sobrevivência multiestado. Análise de dados de cancro da mama.” Trabalho inserido no programa de Diploma de Estudos Avançados do Departamento de Estatística e Investigación Operativa da University of Santiago de Compostela, Spain. Conclusion in July 2009.

 

[Msc] Alda Marisa Ribeiro Fernandes, “Análise de dados em Modelos de estados múltiplos”, Master in Statistics, University of Minho. Concluded in July 2011.

[Msc] Artur Agostinho Araújo, cujo tema é “Estimação da função de distribuição bivariada na presença de censura”, Master in Statistics, University of Minho. Concluded in December 2012.

[Msc] Ilídio Miguel Sousa Andrade Pereira, cujo tema é “Atitudes face à estatística em estudantes de ciências da saúde”, Master in Statistics, University of Minho.  Concluded in December 2012.

[Msc] Edgar Martins Mesquita, cujo tema é “Estudos Bioestatísticos em Linfomas e Leucemias Agudas”, Master in Statistics, University of Minho.  Concluded in October 2013.

[Msc] Miguel Basto Pereira, cujo tema é “Estimação da Sensibilidade, da Especificidade e da curva ROC”, Master in Statistics, University of Minho.  Concluded in December 2013.

[Msc] Andreia Catarina de Sousa Gonçalves, “Estimação da Função de Sobrevivência em dados de eventos recorrentes com censura pela direita”, Mestrado em Estatística, University of Minho. concluded in January 2016.

[Msc] Paula Rosa Silva Lopes, “Estudo de sobrevivência de doentes com cancro de colo de útero”, Master in Statistics, University of Minho. Concluded in March 2017.

[Msc] Ana Beatriz Sampaio e Castro Lapa Carneiro, “Estimação de distribuições multivariadas na presença de censura pela direita”. Concluded in December 2017.

[Msc] Carla Sofia Garcia Soares Ferreira, com o trabalho “Estudo da Prevalência das doenças lisossomais em Portugal”. Concluded in December 2018.

[Msc] Renato Fernandes dos Santos, com o trabalho “Análise estatística a variáveis relacionadas com as especificações de pneus e respetivos testes”. Concluded in December 2019.

[Msc] Giulia Rizzo, com o trabalho “Analysis of survival data: German Breast Cancer Study” Concluded in July 2020.

[Msc] Yoann Folha, “Análise de tendências e determinantes do nível de conhecimento do HIV/AIDS em Moçambique”. Concluded in March 2021.

[Msc] João Rego, “Avaliação de Metodologias de Controlo de Confidencialidade: uma aplicação com bases de microdados para efeitos de investigação”. Ongoing.

 

 

 

 

 

Refereeing

SIM (Statistics in Medicine).

LiDA (Lifetime Data Analysis).

JIRSS (Journal of the Iranian Statistical Society).

JSS (Journal of Statistical Software).

AISM (Annals of the Institute of Statistical Mathematics).

SPE (Sociedade Portuguesa de Estatística).

JCS (Journal of Computational Statistics).

SRE (Scientific Research and Essays).

SPL (Statistics & Probability Letters).

JBD (Journal of Biological Dynamics).

SMMR (Statistical Methods in Medical Research)

BIOM (Biometrics)

BIOMJ (Biometrical Journal)

CSSC (Communications in Statistics - Simulation and Computation)

CISTI (Iberian Conference on Information Systems and Technologies)

REVSTAT

TEST

SJS (Scandinavian Journal of Statistics)

SAJ (Scandinavian Actuarial Journal)

ISNPS (International Society for NonParametric Statistics)

The R Journal

BMC Medical Research Methodology

Acta Medica Portuguesa

 

Experiences in the organization of activities I+D

Chair of the 34th edition of the International Workshop on Statistical Modelling (IWSM2019www.iwsm2019.org), July 7-12 2019, Guimarães, Portugal.

 

Secretary and Treasurer of the Organizing Committee for the “I Congresso de Estatística e Investigação Operacional da Galiza e Norte de Portugal VII Congreso Galego de Estatística e Investigación de Operacións, Guimarães, Portugal, October 26-28, 2005”.

 

Member of the organizing committee of theXI Conferência Espanhola e Primeiro Encontro Ibero Americano de Biometria”, Salamanca, Spain, July 20- 22, 2007”.

 

Member of the scientific committee of the workshop StaM2010 “Statistical Modelling: Challenges in Health”, Lisbon, Portugal, May 9-12, 2010.

 

Organization of the invited session “Modelos Multiestado” from the Conference SEIO (Sociedad Española de Estadística e Investigación Operativa), A Coruña, Spain, September 14-17, 2010.

 

Member of the organizing committee of the workshop “VI International Workshop on Spatio-Temporal Modelling (METMAVI)”, Guimarães, Portugal, September 12-14, 2012.

 

Member of the scientific committee of the workshop “1.º Fórum de Estatística na Universidade do Minho”, NEEUM, School of Sciences, University of Minho, Guimarães, Portugal, September 25th 2012.

 

Member of the organizing committee of the workshop Workshop Statistical Modelling in Medical and Environmental Sciences”, Guimarães, Portugal, December 13, 2012.

 

Member of the organizing committee of the Conference “JOCLAD 2013 - XX Jornadas de Classificação e Análise de Dados”, Guimarães, Portugal, April 11-13, 2013.

 

Member of the organizing committee of the workshop “Second Meeting on Statistical Modeling in Medical and Environmental Sciences”, Guimarães, Portugal, October 3-4, 2013.

 

Member of the scientific committee of the Conference “I Encontro Português de Biometria e I Encontro Luso-Galaico de Biometria”, Braga, Portugal, July 14-16, 2013.

 

Member of the organizing committee of the workshop “Second Meeting on Statistical Modeling in Medical and Environmental Sciences”, Guimarães, Portugal, October 3-4, 2013.

 

Member of the organizing committee of the workshop “Statistics and Applications”, Guimarães, Portugal, October 15-16, 2014.

 

Organization of the invited session “New software developments for competing risks and multi-state models” of the Conference ERCIM 2014, Pisa, Italy, December 6-8, 2014.

 

Member of the scientific committee of the workshop “One-Day Workshop on Statistics Analysis”, Lisbon, Portugal, January 27, 2017.

 

Member of the scientific committee of the “33rd International Workshop on Statistical Modelling”, Bath, England, July 2018.

 

Chair of the “34rd International Workshop on Statistical Modelling”, Guimarães, Portugal, July 2019.

 

Member of the scientific committee of the “35th International Workshop on Statistical Modelling”, Bilbao, Spain, July 2020.

 

Member of the scientific committee of the “25th National Congress of the Portuguese Statistical Society”, November 2020.

 

 

 

 

Services to community
Project for the SIC (Portuguese) television involving software creation, development of statistical methods and advanced optimization techniques. (with Fernando Fontes and Paulo Pereira).

 

Coordination of Projects / Funding

[Coordinator]  FCT (Portuguese Foundation for Science and Technology) project Statistical Methods in Clinical Research: Spatial, Longitudinal and Survival Studies”, with reference PTDC/MAT/104879/2008. Project funded with 44.976,00 euros.

 

[Co-PI]  FCT (Portuguese Foundation for Science and Technology) project Long Time Health: Modelos Conjuntos para Dados Longitudinais e Tempo-até-Evento para as Ciências da Saúde”, with reference PTDC/MAT-STA/28248/2017.

 

 

[Coordinator] Project to IGIF/ACSS (Institute of Information and Financial Management of Health) “Nursing Classification System of Patients: Creation of instruments for the Classification of Patients in Nursing in the areas of Pediatric Oncology, Injuries cord injury (acute phase) and Cardiology Intensive. Project funded with 23,558.41 euros.

 

[Member] Project “PREFERENTIAL - Improving spatial estimation and survey design through preferential sampling in fishery and biological applications”.  FCT - Programa 2017 - 02/SAICT/2017. Projeto com referência PTDC/MAT-STA/28243/2017. Investigador principal: Raquel Menezes.

[Member] Project “Contribuição dos Fatores Psicológicos na Cura da Ulcera do Pé Diabético, em Indicadores Fisiológicos de Prognóstico de Cura, e Qualidade de Vida: Um Estudo Longitudinal Randomizado de Avaliação de Eficácia”.  Projeto FCT 2017 (H2020) com referencia 02-SAICT-2017 (FCT). Investigador Principal: Maria da Graça Pereira Alves. Project funded with 187.915,67 €

[Member] Project “New contributions in semiparametric regression and applications in agricultural field trials, epidemiological risk assessment, and marine ecology”.  Ministerio de Economía, Industría y Competitividad (Espanha) referencia MTM2017-82379-R. Investigador principal: María Xosé Rodríguez ÁLvarez e Dae-Jin Lee. Project funded with 50.000,00 euros. 2018 - 2020.

 

[Member] Project “Inferencia en Modelos Aditivos Generalizados: Extensiones al Analisis ROC con Covariables, Regresion Cuantil y Analisis de Supervivencia. Aplicaciones en Medicina y Biologia”. Ministerio de Educación y Ciencia (Espanha) MTM2011-28285-C02-01. Fondos FEDER (Conv. Publica). Investigador principal: Carmen Cadarso Suárez. Project funded with 96.558,00 euros. 2012 - 2014.

[Member] Project Espaços urbanos: dinâmicas demográficas e sociais (séculos XVII-XX)”, with reference PTDC/HIS-HIS/099228/2008. Project financed with 142.989,00 euros. Beginning in March 2010. Principal Researcher: Carlota Maria Fernandes Santos. Duration: 18 months.

[Member] Project “Modelos Aditivos Generalizados en Estudios de Asociación, Predicción y Clasificación. Aplicaciones en Medicina y Biologia”. Ministerio de Educación y Ciencia (Espanha) MTM2008-01603/MTM. Fondos FEDER (Conv. Publica). Project funded with 88.300 euros. 2009 - 2011

[Member] Project “Census Vivo”, ciência viva VI with reference CV/PVI/0782 Portugal (concluded in 2007). Project funded with 25.000 euros.

 

[Member] Project “Inferencia Estadística en Modelos Aditivos Generalizados y Extensiones. Aplicaciones a la Fisiología, Epidemiología y Radiología”. Ministerio de Educación y Ciencia (Espanha). Fondos FEDER (Conv. Publica). (concluded in 2008). Project funded with 56.900 euros.

 

[Member] Project “Formación de una Red Nacional de Bioestadística”. Ministerio de Ciencia e Innovación (Espanha) MTM2010-09213-E. Principal Researcher: Carmen Cadarso Suárez. Duration: 12 months.

 

[Member] Project “Census Vivo”, ciência viva VI with reference CV/PVI/0782 Portugal (with conclusion in 2007). Principal Researcher: Bruno Sousa. Project financed with 25.000 euros.

 

[Member] Project “Elemento do projetoInferencia  Estadística en Modelos Aditivos Generalizados y Extensiones. Aplicaciones a la Fisiología, Epidemiología y Radiología”. Ministerio de Educación y Ciencia (Espanha). Fondos FEDER (Conv. Publica). Investigador principal: Carmen Cadarso Suárez. Project funded with 56.900 euros. 2005- 2017.

 

 

 


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Current and Past Professional Links

Statistics and Operational Research Department in Santiago de Compostela University, where I was registered as a PhD student and where my official supervisor Prof.Carmen Cadarso-Suárez. My other official PhD supervisor is Prof. Jacobo de Uña-Álvarez from Vigo University.


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other Links

·      IWSM2019

·      Biostatnet

·      International Association for Statistical Computing, IASC-ISI

·      Associação Portuguesa de Classificação e Análise de Dados, CLAD

·      Sociedade Portuguesa de Estatística, SPE

·      R

·      Quick-R

·      Portalaction

·      Statistics Calculator Online

·      Quick Calculator Online

·      Wolfram Research: Probability and Statistics, Integral Calculator, Derivative Calculator

·      Diagnostic Test Evaluation Calculator

·      Statistical Computation Online: Clinical Calculator and many other tests

·      Compendium of Common Probability Distributions

·      Probability Calculator

·      Wikipedia


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Page creation at 2006. Last update at June 2021.